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Core needle biopsy pathology report

Record type: surgical pathology report, as downloaded from the patient portal. Stand-in for: surgical-pathology-report-SP26-XXXXX.pdf (invented document), page 1 of 1. Reporting clinician: pathologist, regional hospital pathology department. Procedure performed by: breast radiologist, community breast imaging center, 08/22/2026.

SURGICAL PATHOLOGY REPORT

Collected: 08/22/2026 · Received: 08/22/2026 · Reported: 08/26/2026

CLINICAL HISTORY: 64-year-old woman. Right breast 10 o’clock, 4 cm from nipple, 1.8 cm irregular spiculated mass, BI-RADS 5. Ultrasound-guided core needle biopsy with clip placement.

SPECIMEN: A. Right breast, 10 o’clock, ultrasound-guided core needle biopsy.

FINAL DIAGNOSIS:

A. RIGHT BREAST, 10 O’CLOCK, CORE NEEDLE BIOPSY:

  • INVASIVE BREAST CARCINOMA OF NO SPECIAL TYPE (DUCTAL), NOTTINGHAM HISTOLOGIC GRADE 2 (tubule formation 3, nuclear pleomorphism 2, mitotic count 1; total score 6 of 9).
  • Ductal carcinoma in situ, intermediate nuclear grade, solid and cribriform patterns, present in association with the invasive carcinoma.
  • Lymphovascular invasion: not identified in the sampled cores.
  • Biopsy site changes present.

COMMENT: Prognostic and predictive marker studies (estrogen receptor, progesterone receptor, HER2, and Ki-67) have been ordered on block A1 and will be reported in a separate addendum. Definitive tumor size, margin status, and lymph node status cannot be determined on a core biopsy and await surgical excision if performed.

GROSS DESCRIPTION: Received in formalin labeled with the patient’s name and “right breast 10 o’clock” are four tan-white to tan-pink cylindrical tissue cores measuring 0.8 to 1.5 cm in length and 0.1 cm in diameter. Submitted entirely in one cassette (A1).

MICROSCOPIC DESCRIPTION: Sections show cores of fibrous breast tissue infiltrated by nests, cords, and occasional tubules of malignant epithelial cells with moderately pleomorphic nuclei and moderate amounts of eosinophilic cytoplasm, eliciting a desmoplastic stromal reaction. Mitotic figures are infrequent. Adjacent ducts are expanded by a proliferation of intermediate-grade malignant cells in solid and cribriform patterns without necrosis, consistent with ductal carcinoma in situ. No lymphovascular invasion is identified in the material examined.

Electronically signed by the reporting pathologist, 08/26/2026 16:42.

The receptor results referred to in the comment were reported on 09/02/2026: pathology addendum.