An illustration · invented records · this source is real
Using the 21-gene assay from core needle biopsies to choose neoadjuvant therapy for breast cancer: A multicenter trial
Bear HD, Wan W, Robidoux A, Rubin P, et al. (2017). Journal of Surgical Oncology. PubMed 28407247 · DOI 10.1002/jso.24610 · PubMed record
What kind of source: Small multicenter feasibility trial. Where it sits in the summary: Still being studied. Back to the summary
What it says, in plain language
Shows the test can be run on a core needle biopsy before surgery, in a study that used it to choose treatment given before surgery. This is a different use from the after-surgery decision in Mom’s case.
Source access: the full text was read as a PubMed Central author manuscript. It is linked rather than reproduced because redistribution is not permitted for this copy. Open the PubMed record and follow its PMC link.
The exact words we relied on
“Core needle biopsy blocks were tested.” — PMID:28407247, Abstract, Methods
“Using the RS to guide NST is feasible.” — PMID:28407247, Abstract, Conclusions
How these quotes were checked
Follow the passage links above to the included paper or public source record.
Full text, author manuscript. The publicly available PMC author manuscript was retrieved on 2026-09-08 and read. Abstract quotes were checked against the cached PubMed record; body-text quotes were checked by exact string match against that manuscript. An author manuscript can differ in wording from the final journal version.
Limits of this source
Sixty-four patients; a feasibility study about pre-surgery treatment, not a test of outcomes. Two published errata exist. The 2021 erratum (PubMed 34314518, read 2026-09-10) reclassifies one patient’s surgical result and revises part of Table 2; the authors state it changes neither the statistical significance nor the conclusions, and neither quote above depends on it. The 2018 erratum (PubMed 30295942) has not been read; the publisher’s page could not be opened by our tools.
Review
Reviewed by Sarah Kiselycznyk · September 10, 2026. Review scope and verification method: How we researched this.